Microarray data analysis and mining approaches
نویسندگان
چکیده
منابع مشابه
Microarray data analysis and mining approaches.
Microarray based transcription profiling is now a consolidated methodology and has widespread use in areas such as pharmacogenomics, diagnostics and drug target identification. Large-scale microarray studies are also becoming crucial to a new way of conceiving experimental biology. A main issue in microarray transcription profiling is data analysis and mining. When microarrays became a methodol...
متن کاملMicroarray data analysis and mining.
DNA microarray is an innovative technology for obtaining information on gene function. Because it is a high-throughput method, computational tools are essential in data analysis and mining to extract the knowledge from experimental results. Filtering procedures and statistical approaches are frequently combined to identify differentially expressed genes. However, obtaining a list of differentia...
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The advent of gene expression microarray technology enables the simultaneous measurement of expression levels for thousands or tens of thousands of genes in a single experiment (Schena, et al., 1995). Analysis of gene expression microarray data presents unprecedented opportunities and challenges for data mining in areas such as gene clustering (Eisen, et al., 1998; Tamayo, et al., 1999), sample...
متن کاملMicroarray Data Analysis and Mining Tools
Microarrays are one of the latest breakthroughs in experimental molecular biology that allow monitoring the expression levels of tens of thousands of genes simultaneously. Arrays have been applied to studies in gene expression, genome mapping, SNP discrimination, transcription factor activity, toxicity, pathogen identification and many other applications. In this paper we concentrate on discuss...
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In recent years, microarray gene expression studies have been actively pursued for extracting significant biological knowledge hidden under a large volume of gene expression profiles accumulated by DNA microarray experiments. Particularly great attentions have been paid to a variety of data mining schemes for gene function discovery [Eisen et al., 1998], disease diagnosis [Saiki et al., 2008], ...
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ژورنال
عنوان ژورنال: Briefings in Functional Genomics and Proteomics
سال: 2008
ISSN: 1473-9550,1477-4062
DOI: 10.1093/bfgp/elm034